Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070520 | 0.85 | ADORA1 (0.46) | ASIC3CD274ALDH1A1CYP3A4TSHR | |
| SCHEMBL31070657 | 0.76 | CHRNB2 (0.48) | ASIC3CD274ALDH1A1CYP3A4TDP2 | |
| SCHEMBL29543416 | 0.73 | ASIC3 (0.56) | ASIC3HTR2AHTR2CHTR2BTDP2 | |
| SCHEMBL31070521 | 0.72 | CD274 (0.63) | CD274HTR2CHTR2BCYP3A4 | |
| SCHEMBL1705264 | 0.70 | CYP3A4 (0.59) | HTR2AHTR2CHTR2BALDH1A1CYP3A4 | |
| SCHEMBL30040451 | 0.70 | CYP3A4 (0.59) | HTR2AHTR2CHTR2BALDH1A1CYP3A4 | |
| SCHEMBL382917 | 0.70 | HTR2C (0.50) | HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL31463205 | 0.69 | HTR2C (0.60) | HTR2AHTR2CHTR2BALDH1A1TLR9 | |
| SCHEMBL21598595 | 0.69 | ASIC3 (0.55) | ASIC3HTR2AHTR2CHTR2BTDP2 | |
| Hydrochloric Acid SCHEMBL31193341 | 0.68 | CYP3A4 (0.56) | HTR2AHTR2CHTR2BALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |