Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506880 | 0.95 | CALCRL (0.52) | CALCRLMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL31122250 | 0.91 | CALCRL (0.53) | CALCRLMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL29634931 | 0.90 | CALCRL (0.53) | CALCRLMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL31122251 | 0.89 | CALCRL (0.52) | CALCRLMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL29634944 | 0.86 | CALCRL (0.54) | CALCRLMAPK8MAPK9MAPK10REN | |
| SCHEMBL29600734 | 0.85 | CALCRL (0.51) | CALCRLMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL29634976 | 0.85 | MAPK8 (0.54) | CALCRLMAPK8MAPK9MAPK10REN | |
| SCHEMBL30150553 | 0.84 | REN (0.52) | CALCRLKEAP1RENBACE1 | |
| SCHEMBL29430213 | 0.83 | CALCRL (0.55) | CALCRLMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL29662137 | 0.82 | CTSC (0.51) | CALCRLRENCTSCGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754937-A | Cyclic polypeptide compound and application thereof | 晶核生物医药科技(南京)有限公司 | 2024-10-11 | — | — | CN | disclosed |
| WO-2024198836-A1 | CYCLIC POLYPEPTIDE COMPOUNDS AND USE THEREOF | 晶核生物医药科技(南京)有限公司 | 2024-10-03 | — | — | WO | disclosed |