Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767352 | 1.00 | TKT (0.33) | TKTSLC6A2HTR2ASLC6A4HRH1 | |
| SCHEMBL5748559 | 0.75 | ALDH1A1 (0.35) | TKT | |
| SCHEMBL5748105 | 0.73 | RIPK1 (0.32) | TKT | |
| SCHEMBL5746427 | 0.72 | CTRC (0.44) | — | |
| SCHEMBL31583423 | 0.71 | PDCD1LG2 (0.32) | TKT | |
| SCHEMBL21767557 | 0.71 | SLC6A2 (0.51) | TKTSLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL31072045 | 0.71 | SLC6A2 (0.51) | TKTSLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL845810 | 0.71 | TKT (0.39) | TKT | |
| SCHEMBL4543311 | 0.71 | SIRT2 (0.31) | — | |
| SCHEMBL846253 | 0.71 | TKT (0.31) | TKT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878533-A | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-112805001-B | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-07-23 | — | — | CN | disclosed |