Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190822 | 1.00 | KCNH2 (0.48) | KCNH2CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL3182327 | 0.84 | ADRB2 (0.53) | CYP1A2CYP2D6NFKB1CYP3A4ALDH1A1 | |
| SCHEMBL31084764 | 0.84 | ADRB2 (0.53) | CYP1A2CYP2D6NFKB1CYP3A4ALDH1A1 | |
| SCHEMBL30446181 | 0.81 | CFD (0.46) | KCNH2CYP2D6NFKB1MEN1KMT2A | |
| SCHEMBL20943296 | 0.81 | CFD (0.46) | KCNH2CYP2D6NFKB1MEN1KMT2A | |
| SCHEMBL20943298 | 0.81 | CFD (0.46) | KCNH2CYP2D6NFKB1MEN1KMT2A | |
| SCHEMBL166818 | 0.80 | KCNH2 (0.54) | KCNH2CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL7147316 | 0.80 | KCNH2 (0.54) | KCNH2CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL15497033 | 0.79 | CYP1A2 (0.53) | KCNH2CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL382016 | 0.79 | CYP1A2 (0.53) | KCNH2CYP1A2CYP2D6NFKB1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024183772-A1 | CYCLIC PHOSPHATE COMPOUND AS DRUG FOR REGULATING CHOLESTEROL METABOLISM VIA LIVER DELIVERY AND USE | 浙江柏拉阿图医药科技有限公司 | 2024-09-12 | — | — | WO | disclosed |