Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20943298 | 1.00 | CFD (0.46) | CFDADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL20943296 | 1.00 | CFD (0.46) | CFDADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL14691470 | 0.84 | CFD (0.45) | CFDADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL15675244 | 0.84 | CFD (0.49) | CFDADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL15675029 | 0.83 | CFD (0.48) | CFDADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL10840143 | 0.81 | ADRA2A (0.50) | CFDADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL31074205 | 0.81 | CES2 (0.46) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL31074207 | 0.81 | KCNH2 (0.48) | ADRB1ADRB2AOC3CYP2D6NFKB1 | |
| SCHEMBL3190822 | 0.81 | KCNH2 (0.48) | ADRB1ADRB2AOC3CYP2D6NFKB1 | |
| SCHEMBL7154532 | 0.81 | ADRA2A (0.50) | CFDADRB1ADRA2AADRB3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111434671-B | Liver-specific AMPK agonist and preparation method and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2023-07-11 | — | — | CN | disclosed |