Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17619676 | 0.81 | KDM4E (0.40) | KDM4EDGAT1 | |
| SCHEMBL31074728 | 0.81 | ALDH1A1 (0.32) | ROCK2KDM4EALDH1A1 | |
| SCHEMBL31124031 | 0.75 | GAA (0.45) | KDM4EDGAT1 | |
| SCHEMBL1330672 | 0.73 | DGAT1 (0.38) | ROCK2KDM4EALDH1A1DGAT1 | |
| SCHEMBL29062157 | 0.72 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL31086380 | 0.71 | NPC1 (0.51) | ROCK2LRRK2ROCK1 | |
| SCHEMBL16772774 | 0.67 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL22143932 | 0.67 | CYP1A2 (0.36) | KDM4EALDH1A1DGAT1 | |
| SCHEMBL22125901 | 0.67 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL29062174 | 0.67 | DGAT1 (0.36) | ROCK2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665734-A1 | CYCLIN-DEPENDENT KINASE (CDK2) INHIBITORS | Novartis AG (CH) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024171094-A1 | CYCLIN-DEPENDENT KINASE (CDK2) INHIBITORS | NOVARTIS AG (CH) | 2024-08-22 | — | — | WO | disclosed |