Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806336 | 0.80 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL2608752 | 0.78 | ALDH1A1 (0.40) | DGAT1 | |
| SCHEMBL29062154 | 0.76 | LRRK2 (0.30) | — | |
| SCHEMBL25414871 | 0.74 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL31511396 | 0.73 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL26103766 | 0.73 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL31074751 | 0.72 | ROCK2 (0.32) | DGAT1 | |
| SCHEMBL19806319 | 0.71 | TGFBR1 (0.38) | DGAT1 | |
| SCHEMBL1330672 | 0.69 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL2123505 | 0.69 | CHRM1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262749-A | Aromatic heterocycle substituted compound and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |