Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | CPA1 | P15085 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.48 |
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | YARS1 | P54577 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728566 | 0.92 | OPRD1 (0.56) | OPRD1OPRM1ACEMMECPA1 | |
| SCHEMBL30578955 | 0.90 | LNPEP (0.58) | OPRD1NPY1RNPY2RNPY4RERAP2 | |
| SCHEMBL29534036 | 0.89 | OPRD1 (0.55) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29351277 | 0.87 | OPRD1 (0.54) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL29559026 | 0.86 | NPY4R (0.60) | OPRD1NPY1RNPY2RNPY4R | |
| SCHEMBL32681297 | 0.85 | FOLH1 (0.60) | OPRD1OPRM1ACEMMENPY1R | |
| SCHEMBL29350612 | 0.85 | ACE (0.58) | OPRD1OPRM1ACEMMEOPRK1 | |
| SCHEMBL11040848 | 0.85 | OPRK1 (0.54) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL11040843 | 0.85 | OPRK1 (0.54) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL31276527 | 0.85 | SLC7A5 (0.56) | OPRD1OPRM1ERAP2LNPEPYARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287154-A1 | MC3R AGONIST PEPTIDES | COURAGE THERAPEUTICS, INC. | 2024-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287154-A1 | MC3R AGONIST PEPTIDES | MC3R, MC4R, MC1R | OPRD1 109/4885OPRM1 172/4885ACE 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.