Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 15/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075313 | 0.85 | ALDH1A1 (0.39) | CACNA1HACACB | |
| SCHEMBL31075195 | 0.77 | ACACB (0.43) | ACACBMAPTMEN1KMT2A | |
| SCHEMBL31075246 | 0.76 | F11 (0.40) | ACACBMAPTMEN1KMT2A | |
| SCHEMBL19224705 | 0.75 | AR (0.46) | MAPTMEN1KMT2A | |
| SCHEMBL26969838 | 0.73 | BCL2L1 (0.34) | CACNA1HKMT2A | |
| SCHEMBL19228569 | 0.73 | CACNA1H (0.41) | CACNA1HMEN1KMT2A | |
| SCHEMBL1412434 | 0.71 | MAPK1 (0.40) | MAPTMEN1KMT2A | |
| SCHEMBL17786853 | 0.71 | F11 (0.40) | ACACBMAPT | |
| SCHEMBL17786852 | 0.70 | KLKB1 (0.57) | ACACB | |
| SCHEMBL23370098 | 0.70 | MAPT (0.54) | ACACBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665330-A1 | PLASMA KALLIKREIN INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173196-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |