Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 13/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075280 | 0.85 | CACNA1H (0.42) | CACNA1HACACB | |
| SCHEMBL26969838 | 0.77 | BCL2L1 (0.34) | CACNA1HAOC3TAAR1 | |
| SCHEMBL17610724 | 0.73 | CYP19A1 (0.53) | ALDH1A1POLBLMNA | |
| SCHEMBL31075255 | 0.73 | ALDH1A1 (0.39) | ALDH1A1POLBLMNACASP1ACACB | |
| SCHEMBL31075273 | 0.73 | L3MBTL1 (0.46) | ALDH1A1POLBLMNA | |
| SCHEMBL26969961 | 0.68 | SCD (0.49) | ALDH1A1LMNA | |
| SCHEMBL26969903 | 0.67 | OGA (0.46) | ALDH1A1POLBAOC3ACACBTAAR1 | |
| SCHEMBL23864060 | 0.66 | HTT (0.39) | ALDH1A1POLBLMNA | |
| SCHEMBL184998 | 0.66 | POLB (0.71) | ALDH1A1POLBLMNACASP1 | |
| SCHEMBL16246799 | 0.65 | KLKB1 (0.56) | LMNACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665330-A1 | PLASMA KALLIKREIN INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173196-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |