Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31076421 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL14639099 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6586507 | 0.87 | KMT2A (0.44) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6584885 | 0.87 | KMT2A (0.44) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL16250698 | 0.80 | ALDH1A1 (0.80) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL505806 | 0.79 | KMT2A (0.56) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL29397724 | 0.79 | KMT2A (0.56) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL29503684 | 0.79 | KMT2A (0.56) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL22005816 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDHSD17B10L3MBTL1 | |
| SCHEMBL14638674 | 0.76 | MEN1 (0.38) | ALDH1A1HPGDHSD17B10L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177860-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC (US) | 2024-08-29 | — | — | WO | claimed |
| US-12559784-B2 | In chemico test for toxicity | LEBRUN LABS LLC (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250369032-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC (US) | 2025-12-04 | — | — | US | disclosed |
| US-20250101489-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC | 2025-03-27 | — | — | US | disclosed |
| WO-2024177860-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC (US) | 2024-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559784-B2 | In chemico test for toxicity | ALPP, ALPI, CUTA | ALDH1A1 274/4885TSHR 556/4885HPGD 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.