Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.64 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314168 | 0.91 | RORC (0.77) | RORCPTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31078058 | 0.89 | RORC (0.62) | RORCPTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4880524 | 0.84 | RORC (1.00) | RORCNPC1RAB9ATRPV1SMN1; SMN2 | |
| SCHEMBL5314331 | 0.83 | RORC (0.79) | RORCPTPN1NPC1RAB9ATRPV1 | |
| SCHEMBL12334379 | 0.82 | RORC (0.77) | RORCNPC1RAB9ATRPV1SMN1; SMN2 | |
| SCHEMBL12334581 | 0.82 | RORC (0.77) | RORCNPC1RAB9ATRPV1SMN1; SMN2 | |
| SCHEMBL12334365 | 0.82 | RORC (0.77) | RORCNPC1RAB9ATRPV1SMN1; SMN2 | |
| SCHEMBL5311353 | 0.82 | RORC (0.77) | RORCNPC1RAB9ATRPV1SMN1; SMN2 | |
| SCHEMBL12334375 | 0.82 | RORC (0.77) | RORCNPC1RAB9ATRPV1SMN1; SMN2 | |
| SCHEMBL31078108 | 0.82 | RORC (0.67) | RORCSMN1; SMN2POLBMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245633-A1 | ROR Gamma Agonists as Enhancers of Protective Immunity | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245633-A1 | ROR Gamma Agonists as Enhancers of Protective Immunity | RORC, RORB, RORA | RORC 1/4885PTPN1 409/4885DEGS1 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.