Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31078112 | 0.96 | HTR7 (0.36) | HTR7FGFR1SRCCYP1A2CYP2D6 | |
| SCHEMBL30986474 | 0.85 | MEN1 (0.37) | FGFR1SRCSMN1; SMN2DGAT1MEN1 | |
| SCHEMBL24344854 | 0.80 | MEN1 (0.37) | FGFR1SRCSMN1; SMN2DGAT1MEN1 | |
| SCHEMBL29513592 | 0.80 | MEN1 (0.37) | FGFR1SRCSMN1; SMN2DGAT1MEN1 | |
| SCHEMBL31361147 | 0.79 | PRPS1 (0.40) | DGAT1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL31077988 | 0.78 | BRD4 (0.33) | DGAT1MEN1KMT2ABRD4CREBBP | |
| SCHEMBL31078194 | 0.78 | CCNE1 (0.34) | FGFR1SRCEGFR | |
| SCHEMBL24344409 | 0.77 | MEN1 (0.45) | DGAT1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2141789 | 0.77 | SRC (0.43) | FGFR1SRCCYP1A2MEN1KMT2A | |
| SCHEMBL30986429 | 0.76 | PRPS1 (0.40) | DGAT1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642535-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS SIK MODULATORS | F. Hoffmann-La Roche AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024141443-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS SIK MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | disclosed |