Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 2/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31078515 | 0.84 | PDE4B (0.48) | TOP2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL31078577 | 0.81 | DNMT1 (0.33) | ABHD6EHMT2P2RX3P2RX2 | |
| SCHEMBL31078332 | 0.78 | ATR (0.34) | P2RX3P2RX2 | |
| SCHEMBL31078846 | 0.76 | PDE4B (0.35) | TOP2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30812200 | 0.76 | PDE4B (0.44) | ABHD6EHMT2P2RX3P2RX2OXTR | |
| SCHEMBL31078732 | 0.75 | IKBKE (0.41) | PDE4BSTS | |
| SCHEMBL25295322 | 0.74 | ABHD6 (0.46) | ABHD6OXTRAVPR1ATOP2APDE4B | |
| SCHEMBL16770922 | 0.73 | SCN9A (0.41) | ABHD6OXTRAVPR1AMGLL | |
| SCHEMBL31079077 | 0.72 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DSTS | |
| SCHEMBL31078623 | 0.72 | ROCK2 (0.37) | TOP2APDE4BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |