Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079823 | 0.94 | TSHR (0.45) | LMNAALDH1A1TSHRL3MBTL1PABPC1 | |
| SCHEMBL31079601 | 0.90 | LMNA (0.46) | LMNAALDH1A1TSHRL3MBTL1PABPC1 | |
| SCHEMBL31079632 | 0.90 | LMNA (0.46) | LMNAALDH1A1TSHRL3MBTL1PABPC1 | |
| SCHEMBL11526413 | 0.85 | TSHR (0.54) | LMNAALDH1A1TSHRL3MBTL1PABPC1 | |
| SCHEMBL11526472 | 0.85 | TSHR (0.54) | LMNAALDH1A1TSHRL3MBTL1PABPC1 | |
| SCHEMBL11524968 | 0.85 | TSHR (0.54) | LMNAALDH1A1TSHRL3MBTL1PABPC1 | |
| SCHEMBL29825333 | 0.84 | ZDHHC7 (0.38) | LMNAZDHHC7USP2 | |
| SCHEMBL11598804 | 0.83 | TSHR (0.56) | LMNAALDH1A1TSHRL3MBTL1PABPC1 | |
| SCHEMBL29824791 | 0.81 | ZDHHC7 (0.34) | ALDH1A1ZDHHC7 | |
| SCHEMBL29056390 | 0.80 | CA2 (0.50) | LMNATSHRZDHHC7USP2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | UNIV MICHIGAN REGENTS (US) | 2024-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | TNNI3, ALDH2, ALDH5A1 | LMNA 221/4885ALDH1A1 54/4885TSHR 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.