Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LOX | P28300 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325260 | 0.83 | CA2 (0.78) | CA2LOXALDH1A1POLBCYP3A4 | |
| SCHEMBL8092429 | 0.82 | CA2 (0.60) | CA2LOXALDH1A1POLBCYP3A4 | |
| SCHEMBL2054700 | 0.81 | TDP1 (0.52) | CA2TDP1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL11050771 | 0.80 | HTT (0.57) | CA2TDP1ALDH1A1POLBHTT | |
| SCHEMBL7869982 | 0.79 | TDP1 (0.50) | TDP1ALDH1A1POLBHTTKMT2A | |
| SCHEMBL7869979 | 0.79 | HTT (0.55) | CA2TDP1ALDH1A1POLBHTT | |
| SCHEMBL3696887 | 0.78 | TDP1 (0.57) | TDP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7011024 | 0.78 | TDP1 (0.49) | CA2TDP1ALDH1A1POLBCYP3A4 | |
| SCHEMBL10792219 | 0.77 | CA2 (0.69) | CA2LOXALDH1A1POLBCYP3A4 | |
| SCHEMBL10592713 | 0.76 | TDP1 (0.55) | CA2TDP1ALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100274058-A1 | Process for Preparation of 2-[Vinyl (Hetero) Arylsulphonyl] Ethanol Derivatives | UNIVERSITY OF DURHAM (GB) | 2010-10-28 | — | — | US | claimed |
| EP-1989181-A1 | PROCESS FOR THE PREPARATION OF 2-[VINYL (HETERO) ARYL SULPHONYL]ETHANOL DERIVATIVES | UNIVERSITY OF DURHAM (GB) | 2008-11-12 | — | — | EP | claimed |
| WO-2007093772-A1 | PROCESS FOR THE PREPARATION OF 2- [VINYL (HETERO) ARYL SULPHONYL] ETHANOL DERIVATIVES | UNIVERSITY OF DURHAM (GB) | 2007-08-23 | — | — | WO | claimed |
| US-20100274058-A1 | Process for Preparation of 2-[Vinyl (Hetero) Arylsulphonyl] Ethanol Derivatives | UNIVERSITY OF DURHAM (GB) | 2010-10-28 | — | — | US | disclosed |
| US-20100274058-A1 | Process for Preparation of 2-[Vinyl (Hetero) Arylsulphonyl] Ethanol Derivatives | UNIVERSITY OF DURHAM (GB) | 2010-10-28 | — | — | US | disclosed |
| US-20100274058-A1 | Process for Preparation of 2-[Vinyl (Hetero) Arylsulphonyl] Ethanol Derivatives | UNIVERSITY OF DURHAM (GB) | 2010-10-28 | — | — | US | disclosed |
| US-20100010266-A1 | Resin cross-linking | THE UNIVERSITY OF MANCHESTER (GB) | 2010-01-14 | — | — | US | disclosed |
| US-20100010266-A1 | Resin cross-linking | THE UNIVERSITY OF MANCHESTER (GB) | 2010-01-14 | — | — | US | disclosed |
| US-20100010266-A1 | Resin cross-linking | THE UNIVERSITY OF MANCHESTER (GB) | 2010-01-14 | — | — | US | disclosed |
| US-7598323-B2 | Resin cross-linking | THE UNIVERSITY OF MANCHESTER (GB) | 2009-10-06 | — | — | US | disclosed |
| US-7598323-B2 | Resin cross-linking | THE UNIVERSITY OF MANCHESTER (GB) | 2009-10-06 | — | — | US | disclosed |
| US-7598323-B2 | Resin cross-linking | THE UNIVERSITY OF MANCHESTER (GB) | 2009-10-06 | — | — | US | disclosed |
| EP-1989181-A1 | PROCESS FOR THE PREPARATION OF 2-[VINYL (HETERO) ARYL SULPHONYL]ETHANOL DERIVATIVES | UNIVERSITY OF DURHAM (GB) | 2008-11-12 | — | — | EP | disclosed |
| EP-1565513-B1 | RESIN CROSS-LINKING | UNIV MANCHESTER (GB) | 2008-07-09 | — | — | EP | disclosed |
| EP-1565513-B1 | RESIN CROSS-LINKING | UNIV MANCHESTER (GB) | 2008-07-09 | — | — | EP | disclosed |
| US-20080125572-A1 | POLYCHLOROPRENE-BASE LATEX AND METHOD FOR PRODUCING IT | TOSOH CORPORATION (JP) | 2008-05-29 | — | — | US | disclosed |
| WO-2007093772-A1 | PROCESS FOR THE PREPARATION OF 2- [VINYL (HETERO) ARYL SULPHONYL] ETHANOL DERIVATIVES | UNIVERSITY OF DURHAM (GB) | 2007-08-23 | — | — | WO | disclosed |
| US-20060009572-A1 | Resin cross-linking | AKZO NOBEL COATINGS INTERNATIONAL B. V. (NL) | 2006-01-12 | — | — | US | disclosed |
| EP-1565513-A1 | RESIN CROSS-LINKING | The University of Manchester (GB) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004048448-A1 | RESIN CROSS-LINKING | THE UNIVERSITY OF MANCHESTER (GB) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010266-A1 | Resin cross-linking | RXRG, RXRB, RXRA | CA2 2782/4885TDP1 3453/4885LOX 72/4885 |
| US-20100274058-A1 | Process for Preparation of 2-[Vinyl (Hetero) Arylsulphonyl] Ethanol Derivatives | SMARCC2, SMARCC1, PYM1 | CA2 2521/4885TDP1 2498/4885LOX 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.