SCHEMBL2054700

SCHEMBL2054700

C=Cc1ccc(S(=O)(=O)CCC)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 4/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP3A4 P08684 1/20 0.42
GAA P10253 2/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
PSIP1 O75475 2/20 0.38
CA2 P00918 2/20 0.36
MMP13 P45452 2/20 0.36
PNMT P11086 1/20 0.35
CYP1A2 P05177 1/20 0.35
MMP8 P22894 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
MMP2 P08253 1/20 0.35
MMP7 P09237 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3696887 0.86 TDP1 (0.57) TDP1ALDH1A1CYP2C9CYP2C19CYP3A4
SCHEMBL2054720 0.82 ALDH1A1 (0.44) ALDH1A1CYP2C9CYP2C19CYP3A4GAA
SCHEMBL3107979 0.81 CA2 (0.58) TDP1ALDH1A1CYP2C9CYP2C19CYP3A4
SCHEMBL25674520 0.77 TDP1 (0.52) TDP1ALDH1A1CYP2C9CYP2C19CYP3A4
SCHEMBL9067743 0.77 CA12 (0.62) TDP1ALDH1A1CYP2C9CYP2C19GAA
SCHEMBL11050771 0.77 HTT (0.57) TDP1ALDH1A1GAACA2MEN1
SCHEMBL10592713 0.76 TDP1 (0.55) TDP1ALDH1A1CYP2C9CYP2C19CYP3A4
SCHEMBL9067555 0.76 ALDH1A1 (0.61) TDP1ALDH1A1CYP2C9CA2LMNA
SCHEMBL92881 0.75 ALDH1A1 (0.72) ALDH1A1CYP2C9CYP2C19CYP3A4GAA
SCHEMBL2054690 0.75 ALDH1A1 (0.38) ALDH1A1CYP2C9CYP2C19CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11220062-B2 Water-dispersible thermoplastic material comprising sulfonated copolymer for use in additive manufacturing STRATASYS, INC. (US) 2022-01-11 US claimed
US-20200207025-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. 2020-07-02 US claimed
US-20240191087-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS INC (US) 2024-06-13 US disclosed
US-11939480-B2 Water dispersible sulfonated thermoplastic copolymer for use in additive manufacturing STRATASYS, INC. (US) 2024-03-26 US disclosed
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof TOSOH FINECHEM CORPORATION (JP) 2022-10-04 US disclosed
US-11220062-B2 Water-dispersible thermoplastic material comprising sulfonated copolymer for use in additive manufacturing STRATASYS, INC. (US) 2022-01-11 US disclosed
US-20210348010-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. 2021-11-11 US disclosed
EP-3864093-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING Stratasys, Inc. (US) 2021-08-18 EP disclosed
US-20210237364-A1 METHOD OF TREATING A DISPERSION OF SULFOPOLYMER STRATASYS, INC. 2021-08-05 US disclosed
US-10982043-B2 Recycling and reuse of sulfonated polymer material in additive manufacturing STRATASYS, INC. (US) 2021-04-20 US disclosed
EP-3694939-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING Stratasys, Inc. (US) 2020-08-19 EP disclosed
US-20200207025-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. 2020-07-02 US disclosed
EP-3666753-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF Tosoh Finechem Corporation (JP) 2020-06-17 EP disclosed
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORPORATION (JP) 2020-06-04 US disclosed
WO-2019075107-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. (US) 2019-04-18 WO disclosed
US-20180030234-A1 RECYCLING AND REUSE OF SULFONATED POLYMER MATERIAL IN ADDITIVE MANUFACTURING STRATASYS, INC. 2018-02-01 US disclosed
US-9505713-B2 High-purity sodium p-styrenesulfonate with excellent hue, method for producing the same, poly(sodium p-styrenesulfonate) with excellent hue using the same, and dispersant and synthetic starch for clothing finishing using the poly(sodium p-styrenesulfonate) TOSOH ORGANIC CHEMICAL CO., LTD (JP) 2016-11-29 US disclosed
US-20150246876-A1 HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE) TOSOH ORGANIC CHEMICAL CO., LTD. (JP) 2015-09-03 US disclosed
US-8163956-B2 Inhibitors of GLYT1 transporters MERCK SHARP & DOHME CORP. (US) 2012-04-24 US disclosed
US-20090286765-A1 Therapeutic Agents MERCK SHARP & DOHME (UK) LIMITED (GB) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof SLC7A1, ARSA, STS TDP1 3230/4885ALDH1A1 3039/4885CYP2C9 1433/4885
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF SLC7A1, ARSA, STS TDP1 3230/4885ALDH1A1 3039/4885CYP2C9 1433/4885
US-20090286765-A1 Therapeutic Agents GRIA1, GRIN1, GLRA1 TDP1 2700/4885ALDH1A1 652/4885CYP2C9 2463/4885
US-20150246876-A1 HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE) HPSE, STS, TST TDP1 2501/4885ALDH1A1 3105/4885CYP2C9 1750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.