Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079525 | 0.94 | CYP1A2 (0.46) | KMT2ACYP1A2TSHRALDH1A1TDP1 | |
| SCHEMBL4835509 | 0.87 | CYP1A2 (0.52) | KMT2ACYP1A2TSHRALDH1A1TDP1 | |
| SCHEMBL11514409 | 0.87 | CYP1A2 (0.52) | KMT2ACYP1A2TSHRALDH1A1TDP1 | |
| SCHEMBL31079601 | 0.84 | LMNA (0.46) | KMT2ATSHRALDH1A1HSD17B10LMNA | |
| SCHEMBL31079632 | 0.84 | LMNA (0.46) | KMT2ATSHRALDH1A1HSD17B10LMNA | |
| SCHEMBL11598732 | 0.80 | KMT2A (0.54) | KMT2ACYP1A2TSHRALDH1A1TDP1 | |
| SCHEMBL7971092 | 0.80 | KMT2A (0.54) | KMT2ACYP1A2TSHRALDH1A1TDP1 | |
| SCHEMBL7073725 | 0.79 | CYP1A2 (0.55) | KMT2ACYP1A2TSHRALDH1A1TDP1 | |
| SCHEMBL3819477 | 0.78 | CYP1A2 (0.50) | KMT2ACYP1A2TSHRALDH1A1TDP1 | |
| SCHEMBL3826148 | 0.78 | CYP1A2 (0.50) | KMT2ACYP1A2TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | UNIV MICHIGAN REGENTS (US) | 2024-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | TNNI3, ALDH2, ALDH5A1 | KMT2A 4103/4885CYP1A2 2238/4885TSHR 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.