Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25885549 | 1.00 | HSD11B1 (0.32) | HSD11B1LPAR1LPAR3NR1H2KCNH2 | |
| SCHEMBL25886054 | 0.94 | LPAR1 (0.32) | HSD11B1LPAR1LPAR3 | |
| SCHEMBL25885914 | 0.92 | HSD11B1 (0.32) | HSD11B1LPAR1LPAR3NR1H2KCNH2 | |
| SCHEMBL25887845 | 0.91 | LPAR1 (0.32) | HSD11B1LPAR1LPAR3 | |
| SCHEMBL25885553 | 0.91 | SIGMAR1 (0.36) | HSD11B1LPAR1LPAR3 | |
| SCHEMBL25885915 | 0.90 | LPAR1 (0.31) | HSD11B1LPAR1LPAR3 | |
| SCHEMBL25885544 | 0.89 | ALDH1A1 (0.35) | HSD11B1KCNH2 | |
| SCHEMBL25885922 | 0.89 | LPAR1 (0.32) | HSD11B1LPAR1LPAR3 | |
| SCHEMBL31081847 | 0.88 | POLB (0.32) | NR1H2 | |
| SCHEMBL25886061 | 0.88 | POLB (0.32) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175558-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFONE/SULFOXIMINE-PYRIDINE N-OXIDE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |