Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10273174 | 0.90 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL850463 | 0.84 | LMNA (0.54) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL13065195 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6796229 | 0.77 | MAPT (0.62) | ALDH1A1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL16359012 | 0.77 | HTR2A (0.36) | ALDH1A1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL8382704 | 0.77 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL18751506 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL10792245 | 0.77 | TSHR (0.53) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL5952099 | 0.76 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL9817876 | 0.76 | GRM4 (0.58) | ALDH1A1LMNASMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182747-A2 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |