Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879760 | 0.80 | TSHR (0.33) | MAPTNPSR1TSHRALDH1A1HSD17B10 | |
| SCHEMBL31083015 | 0.77 | ALDH1A1 (0.44) | MAPTNPSR1MAPK1HTTKDM4E | |
| SCHEMBL28323262 | 0.74 | ACHE (0.52) | NQO2MAPTNPSR1AMY1AKDM4E | |
| SCHEMBL3146133 | 0.72 | NQO2 (0.44) | NQO2MAPTNPSR1GAAMAPK1 | |
| SCHEMBL2097204 | 0.72 | ACHE (0.54) | HTR2AMAPTMAPK1MEN1KMT2A | |
| SCHEMBL13065195 | 0.71 | ALDH1A1 (0.46) | MAPTGAACA1KDM4EALDH1A1 | |
| SCHEMBL23580916 | 0.71 | ALOX5 (0.55) | NQO2MAPTNPSR1AMY1AALOX15 | |
| SCHEMBL8351208 | 0.71 | GRM4 (0.46) | MAPTNPSR1GAATSHRMAPK1 | |
| SCHEMBL14125065 | 0.71 | MAPT (0.45) | NQO2MAPTNPSR1AMY1AGAA | |
| SCHEMBL9290196 | 0.71 | MAPT (0.45) | MAPTNPSR1GAATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |