SCHEMBL31083170

SCHEMBL31083170

CC(C)[Si]1(C(C)C)OCC2OCC(OC(=O)c3ccccc3NC(=O)OC(C)(C)C)CC2O[Si](C(C)C)(C(C)C)O1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 1/20 0.34
▸ IDO1 P14902 1/20 0.33
▸ KDM4E B2RXH2 3/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ KLK7 P49862 4/20 0.31
▸ KLK5 Q9Y337 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ HPGD P15428 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ POLB P06746 1/20 0.30
▸ RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25101187 0.75 RXFP1 (0.31) RXFP1IDO1
SCHEMBL28033115 0.68 RXFP1 (0.52) RXFP1IDO1KDM4EALDH1A1MEN1
SCHEMBL29663621 0.67 RXFP1 (0.55) RXFP1IDO1KDM4EALDH1A1MEN1
SCHEMBL9330701 0.66 KMT2A (0.61) RXFP1KDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL12292165 0.64 RXFP1 (0.53) RXFP1IDO1KDM4EALDH1A1MEN1
SCHEMBL12158547 0.64 RXFP1 (0.52) RXFP1IDO1KDM4EALDH1A1MEN1
SCHEMBL1542029 0.63 RXFP1 (0.54) RXFP1IDO1KDM4EALDH1A1MEN1
SCHEMBL29702265 0.62 RXFP1 (0.55) RXFP1KDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL15368377 0.62 RXFP1 (0.59) RXFP1IDO1MEN1KMT2AHTT
SCHEMBL29992092 0.62 RXFP1 (0.59) RXFP1IDO1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024182664-A1 MODIFIED RNA COMPOSITIONS AND RELATED METHODS BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) 2024-09-06 — — WO disclosed
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