Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31084030 | 0.90 | RORC (0.42) | RORCCTSDCTSEBACE1ALOX15 | |
| SCHEMBL31083994 | 0.85 | BACE1 (0.39) | RORCCTSDCTSEBACE1ALDH1A1 | |
| SCHEMBL16874872 | 0.84 | ALDH1A1 (0.51) | RORCCTSDCTSEBACE1ALDH1A1 | |
| SCHEMBL1310475 | 0.82 | RORC (0.49) | RORCALDH1A1MEN1KMT2A | |
| SCHEMBL15212523 | 0.81 | GPR119 (0.38) | RORCGPR119ALOX15 | |
| SCHEMBL17729489 | 0.80 | MAPT (0.51) | RORCGPR119 | |
| SCHEMBL21826368 | 0.80 | HTT (0.52) | RORCALDH1A1ALOX15MEN1NPC1 | |
| SCHEMBL18588038 | 0.80 | RORC (0.41) | RORCALDH1A1GPR119MEN1KMT2A | |
| SCHEMBL569651 | 0.80 | RORC (0.55) | RORCGPR119 | |
| SCHEMBL31084071 | 0.80 | MEN1 (0.52) | RORCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674852-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | Innovstone Therapeutics Limited (CN) | 2026-01-07 | — | — | EP | disclosed |
| CN-118871444-A | Preparation method and application of dihydro-thienopyrimidine derivative | 上海翊石医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2024179493-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | 上海翊石医药科技有限公司 | 2024-09-06 | — | — | WO | disclosed |