SCHEMBL31084036

SCHEMBL31084036

NC(=O)C1(Nc2nc(Cl)nc3c2SCC3)CCC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PDE4B Q07343 1/20 0.30
▸ PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14734141 0.77 LATS1 (0.33) —
SCHEMBL373964 0.74 — —
SCHEMBL187242 0.72 — —
SCHEMBL23068559 0.70 — —
SCHEMBL589616 0.70 ALDH1A1 (0.31) —
SCHEMBL19624252 0.68 — —
SCHEMBL12209146 0.68 PDE4B (0.32) PDE4BPDE4D
SCHEMBL23084550 0.65 NPC1 (0.30) —
SCHEMBL20959214 0.64 KMT2A (0.33) —
SCHEMBL11112029 0.64 PDE4B (0.35) PDE4BPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674852-A1 PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE Innovstone Therapeutics Limited (CN) 2026-01-07 — — EP disclosed
CN-118871444-A Preparation method and application of dihydro-thienopyrimidine derivative 上海翊石医药科技有限公司 2024-10-29 — — CN disclosed
WO-2024179493-A1 PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE 上海翊石医药科技有限公司 2024-09-06 — — WO disclosed
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