Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3111793 | 0.91 | MAPK14 (0.61) | MAPK14TP53 | |
| SCHEMBL3114559 | 0.91 | MAPK14 (0.61) | MAPK14TP53 | |
| SCHEMBL3113468 | 0.91 | MAPK14 (0.63) | MAPK14TP53 | |
| SCHEMBL3109174 | 0.91 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL3106203 | 0.89 | MAPK14 (0.61) | MAPK14TP53 | |
| SCHEMBL3105908 | 0.88 | MAPK14 (0.59) | MAPK14TP53 | |
| SCHEMBL3110088 | 0.87 | MAPK14 (0.61) | MAPK14TP53 | |
| SCHEMBL3120717 | 0.86 | MAPK14 (0.58) | MAPK14TP53 | |
| SCHEMBL3105861 | 0.86 | MAPK14 (0.58) | MAPK14TP53 | |
| SCHEMBL3105870 | 0.84 | MAPK14 (0.63) | MAPK14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256120-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB | 2010-10-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256120-A1 | AMIDE DERIVATIVES | IL1B, IL1A, IL6 | MAPK14 2363/4885TP53 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.