Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25297035 | 1.00 | LMNA (0.51) | LMNANPSR1MAPTALDH1A1HSD17B10 | |
| SCHEMBL25251305 | 0.84 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL31084664 | 0.84 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL2222158 | 0.76 | PTPN1 (0.46) | LMNANPSR1MAPTALDH1A1HSD17B10 | |
| SCHEMBL4714944 | 0.76 | CTSL (0.63) | LMNANPSR1MAPTALDH1A1HSD17B10 | |
| SCHEMBL2555965 | 0.76 | SMN1; SMN2 (0.78) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL17266305 | 0.75 | LMNA (0.67) | LMNANPSR1MAPTALDH1A1HSD17B10 | |
| SCHEMBL18674656 | 0.73 | LMNA (0.64) | LMNANPSR1MAPTALDH1A1HSD17B10 | |
| SCHEMBL18674606 | 0.73 | LMNA (0.68) | LMNANPSR1MAPTALDH1A1HSD17B10 | |
| SCHEMBL14121425 | 0.73 | SMN1; SMN2 (0.59) | LMNANPSR1MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574812-A | Benzenesulfonamide thiazole compounds and their use for the treatment of cancer | 国家医疗保健研究所 | 2024-08-30 | — | — | CN | disclosed |