⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461113 | 0.80 | — | — | |
| SCHEMBL8518573 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL17653600 | 0.73 | CES1 (0.37) | — | |
| SCHEMBL3426528 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL12672981 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL28713605 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL24233285 | 0.68 | CA12 (0.33) | — | |
| SCHEMBL6433810 | 0.67 | — | — | |
| SCHEMBL7706684 | 0.65 | ALDH1A1 (0.43) | — | |
| SCHEMBL3102816 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100255051-A1 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME | BENZ MICHAEL ERIC | 2010-10-07 | — | — | US | disclosed |
| US-7741375-B2 | Polyketal polymers, and methods of making and using same | MEDTRONIC, INC (US) | 2010-06-22 | — | — | US | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |
| EP-1984421-A1 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME | Medtronic, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20070265355-A1 | Polyketal polymers, and methods of making and using same | MEDTRONIC, INC. | 2007-11-15 | — | — | US | disclosed |
| WO-2007098041-A1 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME | MEDTRONIC, INC. (US) | 2007-08-30 | — | — | WO | disclosed |