SCHEMBL31087251

SCHEMBL31087251

c1cc(-c2cnn3cc(-c4ccc(OCCN5CCNCC5)cc4)cnc23)ccn1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 13/20 0.81
FLT1 P17948 12/20 0.81
PRKAB2 O43741 10/20 0.81
PRKAG1 P54619 10/20 0.81
PRKAA2 P54646 10/20 0.81
PRKAA1 Q13131 10/20 0.81
PRKAG3 Q9UGI9 10/20 0.81
PRKAG2 Q9UGJ0 10/20 0.81
PRKAB1 Q9Y478 10/20 0.81
BMP4 P12644 7/20 0.81
LCK P06239 6/20 0.81
SRC P12931 6/20 0.81
EPHA2 P29317 6/20 0.81
RPS6KA1 Q15418 6/20 0.81
MKNK1 Q9BUB5 6/20 0.81
ACVR1 Q04771 2/20 0.81
BMPR1B O00238 1/20 0.81
YES1 P07947 1/20 0.81
THRB P10828 1/20 0.81
EIF2AK2 P19525 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dorsomorphin SCHEMBL463155 0.90 KDR (1.00) KDRFLT1PRKAB2PRKAG1PRKAA2
SCHEMBL2059672 0.89 BMP4 (1.00) KDRFLT1PRKAB2PRKAG1PRKAA2
Dorsomorphin SCHEMBL2119244 0.89 KDR (0.98) KDRFLT1PRKAB2PRKAG1PRKAA2
Dorsomorphin SCHEMBL17845800 0.89 KDR (0.98) KDRFLT1PRKAB2PRKAG1PRKAA2
SCHEMBL2059673 0.88 PRKAB1 (1.00) KDRFLT1PRKAB2PRKAG1PRKAA2
Dorsomorphin SCHEMBL26968137 0.87 KDR (0.94) KDRFLT1PRKAB2PRKAG1PRKAA2
SCHEMBL11953875 0.81 KDR (0.83) KDRFLT1PRKAB2PRKAG1PRKAA2
SCHEMBL12779946 0.80 BMP4 (0.83) KDRFLT1PRKAB2PRKAG1PRKAA2
SCHEMBL13126023 0.80 FLT1 (0.81) KDRFLT1PRKAB2PRKAG1PRKAA2
SCHEMBL13126029 0.80 FLT1 (0.81) KDRFLT1PRKAB2PRKAG1PRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024204596-A1 METHOD FOR PRODUCING RETINAL TISSUE 住友ファーマ株式会社 2024-10-03 WO disclosed