Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | CD4 | P01730 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087747 | 0.91 | KMT2A (0.47) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087745 | 0.89 | KMT2A (0.47) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087748 | 0.88 | ALDH1A1 (0.48) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087754 | 0.87 | MEN1 (0.50) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087744 | 0.86 | KMT2A (0.46) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087749 | 0.84 | LMNA (0.43) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087753 | 0.82 | MAPT (0.53) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087750 | 0.78 | KMT2A (0.47) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL31087741 | 0.74 | KMT2A (0.45) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL7821479 | 0.67 | KMT2A (0.55) | MEN1KMT2ALMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546096-A | Chiral tetrahydropyridazine preparation method of class compound | 扬州大学 | 2024-08-27 | — | — | CN | disclosed |