Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087745 | 0.98 | KMT2A (0.47) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087747 | 0.95 | KMT2A (0.47) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087753 | 0.93 | MAPT (0.53) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087748 | 0.91 | ALDH1A1 (0.48) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087744 | 0.91 | KMT2A (0.46) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087749 | 0.91 | LMNA (0.43) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087752 | 0.87 | MEN1 (0.44) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087750 | 0.81 | KMT2A (0.47) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31087741 | 0.78 | KMT2A (0.45) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL3832921 | 0.72 | NPSR1 (0.55) | MAPTALDH1A1LMNAPOLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546096-A | Chiral tetrahydropyridazine preparation method of class compound | 扬州大学 | 2024-08-27 | — | — | CN | disclosed |