Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 15/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249136 | 0.88 | HTR2A (0.43) | PIK3R1PIK3CA | |
| SCHEMBL31089289 | 0.88 | MPO (0.46) | PIK3R1PIK3CA | |
| SCHEMBL30972910 | 0.83 | HTR1D (0.36) | PIK3R1PIK3CA | |
| SCHEMBL27294746 | 0.80 | GRIN1 (0.35) | PIK3R1PIK3CAWDR5 | |
| SCHEMBL27297250 | 0.80 | PIK3R1 (0.34) | PIK3R1PIK3CAWDR5 | |
| SCHEMBL27296035 | 0.80 | MPO (0.45) | PIK3R1PIK3CA | |
| SCHEMBL29725876 | 0.76 | GRIN1 (0.37) | PIK3R1PIK3CAWDR5 | |
| SCHEMBL13071153 | 0.75 | HRH3 (0.54) | PDE3BPDE3AKMT2A | |
| SCHEMBL27816674 | 0.71 | HTR1D (0.49) | — | |
| SCHEMBL21459566 | 0.69 | HTR1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |