SCHEMBL310899

SCHEMBL310899

O=C(O)c1ccnc(C(=O)OC(=O)c2nccc(C(=O)O)n2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.49
KDM5A P29375 2/20 0.49
KDM3A Q9Y4C1 2/20 0.49
JMJD1C Q15652 1/20 0.49
ALOX15 P16050 2/20 0.43
TSHR P16473 1/20 0.43
ACMSD Q8TDX5 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 4/20 0.41
KDM6B O15054 1/20 0.41
TET3 O43151 1/20 0.41
KDM4A O75164 1/20 0.41
BBOX1 O75936 1/20 0.41
MAPT P10636 1/20 0.41
KDM5C P41229 1/20 0.41
ASPH Q12797 1/20 0.41
KDM4D Q6B0I6 1/20 0.41
TET2 Q6N021 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
KDM7A Q6ZMT4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31126262 0.84 KDM4E (0.55) KDM4EKDM5AKDM3AJMJD1CALOX15
SCHEMBL87765 0.84 KDM4E (0.55) KDM4EKDM5AKDM3AJMJD1CALOX15
Bromide SCHEMBL21331919 0.82 KDM4E (0.53) KDM4EKDM5AKDM3AJMJD1CALOX15
Fluoride SCHEMBL21332111 0.82 KDM4E (0.53) KDM4EKDM5AKDM3AJMJD1CALOX15
Hydrochloric Acid SCHEMBL21173938 0.82 KDM4E (0.53) KDM4EKDM5AKDM3AJMJD1CALOX15
SCHEMBL14782174 0.74 KDM4E (0.46) KDM4EKDM5AKDM3AJMJD1CALDH1A1
SCHEMBL21173946 0.73 P4HA1 (0.47) KDM4EKDM5AKDM3AJMJD1CALOX15
SCHEMBL4823798 0.73 KDM4E (0.41) KDM4EKDM5AKDM3AJMJD1CALOX15
SCHEMBL1505808 0.73 KDM4E (0.57) KDM4EKDM5AKDM3AJMJD1CALOX15
SCHEMBL163233 0.71 KDM4E (0.55) KDM4EKDM5AKDM3AJMJD1CALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN disclosed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed
CN-109790292-A Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2019-05-21 CN disclosed
US-8093349-B2 Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same UBE INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-20100009206-A1 TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, METAL-PLATED TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-01-14 US disclosed