Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486010 | 0.83 | HTT (0.44) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL9354521 | 0.81 | TDP1 (0.41) | TDP1GPR35HTTALDH1A1POLB | |
| SCHEMBL30392759 | 0.81 | TDP1 (0.41) | TDP1GPR35HTTALDH1A1POLB | |
| SCHEMBL3010961 | 0.78 | TDP1 (0.61) | TDP1GPR35ALDH1A1KMT2AMEN1 | |
| SCHEMBL28522110 | 0.78 | TDP1 (0.44) | TDP1GPR35HTTALDH1A1POLB | |
| SCHEMBL31373574 | 0.77 | ALDH1A1 (0.35) | TDP1GPR35HTTALDH1A1MAPT | |
| SCHEMBL26650712 | 0.77 | ALDH1A1 (0.35) | TDP1GPR35HTTALDH1A1MAPT | |
| SCHEMBL29406184 | 0.77 | TDP1 (0.47) | TDP1HTTALDH1A1POLBGFER | |
| SCHEMBL18555673 | 0.77 | MEN1 (0.41) | TDP1HTTALDH1A1MAPTKMT2A | |
| Ammonia Solution, Strong SCHEMBL28763100 | 0.76 | TDP1 (0.58) | TDP1GPR35ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294548-A1 | TRICYCLIC SULTAMS AND SULFAMIDES AS ANTITUMOR AGENTS | PELOTON THERAPEUTICS INC. | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294548-A1 | TRICYCLIC SULTAMS AND SULFAMIDES AS ANTITUMOR AGENTS | DCAF15, RBM39, DCAF1 | TDP1 751/4885GPR35 936/4885HTT 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.