Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.49 |
| ▸ | MMP9 | P14780 | 6/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.44 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | MMP12 | P39900 | 4/20 | 0.40 |
| ▸ | MMP14 | P50281 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GGH | Q92820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517971 | 1.00 | MMP2 (0.49) | MMP2MMP9NOD1FOLH1NAALAD2 | |
| SCHEMBL24164953 | 0.89 | MMP2 (0.47) | MMP2MMP9NOD1FOLH1NAALAD2 | |
| SCHEMBL19895223 | 0.85 | MMP2 (0.45) | MMP2MMP9NOD1FOLH1NAALAD2 | |
| SCHEMBL29159697 | 0.85 | MMP2 (0.45) | MMP2MMP9NOD1FAAHMMP8 | |
| SCHEMBL24393827 | 0.85 | MMP2 (0.39) | MMP2MMP9NOD1FOLH1NAALAD2 | |
| Theanine SCHEMBL23068689 | 0.84 | ALOX15 (0.54) | MMP2MMP9NOD1FOLH1 | |
| SCHEMBL19895221 | 0.84 | NOD1 (0.59) | MMP2MMP9NOD1FAAHMMP8 | |
| SCHEMBL31241202 | 0.84 | NOD1 (0.59) | MMP2MMP9NOD1FAAHMMP8 | |
| SCHEMBL911011 | 0.83 | FOLH1 (0.63) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL73336 | 0.83 | FOLH1 (0.63) | FOLH1NAALAD2RIMKLAGGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118416012-A | Lenvatinib mesylate capsule and preparation method thereof | 山东第一医科大学附属肿瘤医院(山东省肿瘤防治研究院、山东省肿瘤医院) | 2024-08-02 | — | — | CN | disclosed |