Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.38 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376769 | 1.00 | KMT2A (0.53) | KMT2ASIRT6ADORA3TSHRMC4R | |
| SCHEMBL3630126 | 0.80 | P4HTM (0.59) | KMT2ATSHRP4HTMP4HA1MIF | |
| SCHEMBL13664453 | 0.78 | ALDH1A1 (0.47) | KMT2ATSHRP4HTMP4HA1MIF | |
| SCHEMBL15149676 | 0.78 | PRMT1 (0.45) | KMT2A | |
| SCHEMBL4768283 | 0.77 | KMT2A (0.57) | KMT2ASIRT6ADORA3TSHRMC4R | |
| SCHEMBL978974 | 0.76 | NNMT (0.63) | KMT2ASIRT6VNN1NNMTP4HTM | |
| SCHEMBL3163574 | 0.76 | KMT2A (0.55) | KMT2ASIRT6ADORA3TSHRMC4R | |
| SCHEMBL1831265 | 0.76 | KMT2A (0.55) | KMT2ASIRT6ADORA3TSHRMC4R | |
| SCHEMBL20254702 | 0.75 | SLC22A2 (0.33) | KMT2A | |
| SCHEMBL171039 | 0.74 | KMT2A (0.53) | KMT2ASIRT6ADORA3TSHRMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024219794-A1 | SUBSTITUTED ACETYLENE COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE | AVELOS THERAPEUTICS INC. (KR) | 2024-10-24 | — | — | WO | disclosed |