Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aguerin B SCHEMBL29352650 | 0.85 | MAPT (0.54) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10307519 | 0.82 | MAPT (0.43) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Cynaropicrin SCHEMBL349976 | 0.81 | MAPT (0.42) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Cynaropicrin SCHEMBL1711811 | 0.81 | MAPT (0.42) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Cynaropicrin SCHEMBL1711522 | 0.81 | MAPT (0.42) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Desacylcynaropicrin SCHEMBL10307509 | 0.77 | MAPT (0.33) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Desacylcynaropicrin SCHEMBL1712162 | 0.77 | MAPT (0.33) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10307583 | 0.72 | MAPT (0.35) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Isozaluzanin C SCHEMBL17214374 | 0.67 | PKM (0.40) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL18180882 | 0.66 | FNTA (0.45) | MAPTMEN1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574933-A | Methods for treating ornithine carbamoyltransferase (OTC) deficiency | 宾夕法尼亚州大学信托人 | 2024-08-30 | — | — | CN | disclosed |