Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | GPX4 | P36969 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307519 | 0.89 | MAPT (0.43) | MAPTNPC1HTTRAB9AKDM4E | |
| Cynaropicrin SCHEMBL1711522 | 0.87 | MAPT (0.42) | MAPTNPC1HTTRAB9AKDM4E | |
| Cynaropicrin SCHEMBL349976 | 0.87 | MAPT (0.42) | MAPTNPC1HTTRAB9AKDM4E | |
| Cynaropicrin SCHEMBL1711811 | 0.87 | MAPT (0.42) | MAPTNPC1HTTRAB9AKDM4E | |
| SCHEMBL31092250 | 0.85 | MAPT (0.43) | MAPTNPC1HTTRAB9AKDM4E | |
| SCHEMBL10307583 | 0.79 | MAPT (0.35) | MAPTNPC1HTTRAB9AKDM4E | |
| Desacylcynaropicrin SCHEMBL10307509 | 0.77 | MAPT (0.33) | MAPTNPC1HTTRAB9AMITF | |
| SCHEMBL28108662 | 0.76 | MAPT (0.73) | MAPTNPC1HTTRAB9AKDM4E | |
| Molephantin SCHEMBL27163122 | 0.70 | NPC1 (1.00) | MAPTNPC1HTTRAB9AKDM4E | |
| SCHEMBL31273011 | 0.70 | MAPT (0.42) | MAPTNPC1HTTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229204-B2 | Herbicidal composition comprising at least one phenolic active compound | Université de Liège (BE) | 2022-01-25 | — | — | US | claimed |
| US-11229204-B2 | Herbicidal composition comprising at least one phenolic active compound | Université de Liège (BE) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229204-B2 | Herbicidal composition comprising at least one phenolic active compound | DDT, DNPH1, KEAP1 | MAPT 2189/4885NPC1 4123/4885HTT 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.