Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092645 | 0.85 | TDP1 (0.44) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7555551 | 0.85 | TDP1 (0.44) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7272204 | 0.80 | NOTUM (0.42) | TDP1ALDH1A1 | |
| SCHEMBL13990527 | 0.78 | ALDH1A1 (0.34) | TDP1ALDH1A1KDM1AKDM1BMAPT | |
| SCHEMBL23591340 | 0.75 | TDP1 (0.44) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL11684047 | 0.75 | TDP1 (0.39) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7534006 | 0.74 | ALDH1A1 (0.46) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7057611 | 0.72 | TSHR (0.46) | TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL7940907 | 0.72 | AHR (0.44) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL23351729 | 0.71 | KDM1A (0.48) | TDP1ALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431373-B1 | Processes for producing 5-fluorbenzoic acids and their intermediates | ASAHI GLASS CO LTD (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5332851-A | Trichloromethylating a fluorodihalobenzene, reaction with ammonia, hydrolysis of the nitrile | ASAHI GLASS COMPANY LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5241111-A | Trichloromethylating a fluorobenzene, reacting with aqueous ammonia, fluorinating, hydrolyzing | ASAHI GLASS COMPANY LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0431373-A2 | Processes for producing 5-fluorbenzoic acids and their intermediates | ASAHI GLASS COMPANY LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |