SCHEMBL3109280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31370601	1.00	MTNR1A (0.41)	MTNR1AMTNR1BL3MBTL1HTR6PDE4B
	SCHEMBL3101171	0.86	TLR9 (0.49)	L3MBTL1CTSLALDH1A1TLR9
	SCHEMBL29122828	0.84	L3MBTL1 (0.41)	MTNR1AMTNR1BL3MBTL1HTR6PDE4B
	SCHEMBL1748650	0.82	L3MBTL1 (0.39)	MTNR1AMTNR1BL3MBTL1HTR6PDE4B
	SCHEMBL17429443	0.82	LCK (0.39)	L3MBTL1HTR6PDE4BPDE4APDE4C
	SCHEMBL25357981	0.82	L3MBTL1 (0.41)	L3MBTL1HTR6MEN1KMT2APIM1
	SCHEMBL29364313	0.82	L3MBTL1 (0.41)	L3MBTL1HTR6MEN1KMT2APIM1
	SCHEMBL29992688	0.81	AKR1C3 (0.47)	MTNR1AMTNR1BL3MBTL1HTR6MEN1
	SCHEMBL31370660	0.81	HTR6 (0.40)	MTNR1AMTNR1BL3MBTL1HTR6PDE10A
	SCHEMBL1357445	0.81	AKR1C3 (0.47)	MTNR1AMTNR1BL3MBTL1HTR6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.