Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | USP10 | Q14694 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30957331 | 0.86 | GPR35 (0.41) | MAPTATMTDP1MAPK1TSHR | |
| SCHEMBL31094807 | 0.84 | TDP1 (0.42) | MAPTATMTDP1MAPK1TSHR | |
| SCHEMBL7859174 | 0.84 | TSHR (0.53) | MAPTTDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL22070445 | 0.83 | DTYMK (0.50) | MAPTATMTDP1TSHRCYP3A4 | |
| SCHEMBL30957347 | 0.82 | ABCB1 (0.40) | MAPTTDP1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22009916 | 0.81 | SIRT6 (0.47) | MAPTTDP1MAPK1TSHRCYP3A4 | |
| SCHEMBL18311461 | 0.79 | TDP1 (0.56) | MAPTATMTDP1MAPK1TSHR | |
| SCHEMBL23273444 | 0.77 | NPSR1 (0.36) | MAPTATMTDP1TSHRCYP3A4 | |
| SCHEMBL29738072 | 0.77 | ALDH1A1 (0.50) | MAPTTSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL14577245 | 0.77 | BCHE (0.47) | MAPTTDP1MAPK1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208228-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-10-10 | — | — | WO | disclosed |