Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25192812 | 1.00 | KMO (0.38) | KMONOTUMMAPTMAPK1RECQL | |
| SCHEMBL22185266 | 0.85 | PDE2A (0.38) | NOTUMPPARDPPARA | |
| SCHEMBL20589858 | 0.84 | MBOAT4 (0.38) | NOTUM | |
| SCHEMBL22185264 | 0.84 | SCN5A (0.40) | MAPTMAPK1PPARGPPARDPPARA | |
| SCHEMBL4426063 | 0.81 | NOTUM (0.51) | KMONOTUMSLC1A5PPARGPPARD | |
| SCHEMBL4425998 | 0.80 | KMO (0.53) | KMONOTUM | |
| SCHEMBL31095268 | 0.79 | HTR2A (0.43) | KMONOTUMMAPTMAPK1L3MBTL1 | |
| SCHEMBL25194605 | 0.79 | HTR2A (0.43) | KMONOTUMMAPTMAPK1L3MBTL1 | |
| SCHEMBL20588626 | 0.77 | SCN5A (0.40) | MAPTMAPK1RECQLL3MBTL1GRIN2B | |
| SCHEMBL25195272 | 0.76 | DHFR (0.46) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |