⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549138 | 1.00 | — | — | |
| SCHEMBL31503961 | 0.86 | APLNR (0.44) | — | |
| SCHEMBL13052072 | 0.86 | APLNR (0.44) | — | |
| SCHEMBL5226 | 0.80 | — | — | |
| SCHEMBL17903 | 0.80 | — | — | |
| SCHEMBL4573609 | 0.80 | — | — | |
| SCHEMBL310953 | 0.80 | — | — | |
| SCHEMBL385627 | 0.80 | — | — | |
| SCHEMBL336216 | 0.80 | — | — | |
| SCHEMBL646506 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066528-A1 | Method for Synthesizing a Covalent Organic Framework Material | YOCOF MAT SUZHOU CO LTD (CN) | 2025-02-27 | — | — | US | claimed |
| CN-114773556-B | Green solid-phase synthesis method of covalent organic framework material | 耀科新材料(苏州)有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117624521-A | Ionic covalent organic framework material, solid phase synthesis method and application thereof | 耀科新材料(苏州)有限公司 | 2024-03-01 | — | — | CN | claimed |
| WO-2024037615-A1 | IONIC COVALENT ORGANIC FRAMEWORK MATERIAL, SOLID-PHASE SYNTHESIS METHOD THEREOF, AND USE THEREOF | 耀科新材料（天津）有限公司 | 2024-02-22 | — | — | WO | claimed |
| WO-2023124952-A1 | GREEN SOLID-PHASE SYNTHESIS METHOD FOR COVALENT ORGANIC FRAMEWORK MATERIAL | 张振杰 | 2023-07-06 | — | — | WO | claimed |
| CN-114773556-A | Green solid-phase synthesis method of covalent organic framework material | 南开大学 | 2022-07-22 | — | — | CN | claimed |
| EP-3527559-A1 | GAMMA-BUTYROLACTONE COMPOSITION AND METHOD FOR PRODUCING SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-08-21 | — | — | EP | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-9598388-B2 | Method for producing tetrahydrofuran | MITSUBISHI CHEMICAL CORPORATION (JP) | 2017-03-21 | — | — | US | claimed |
| US-20170056398-A1 | SUBSTITUTED PYRIDINES AS P2X3 AND P2X2/3 ANTAGONISTS | ROCHE PALO ALTO LLC (US) | 2017-03-02 | — | — | US | claimed |
| US-20130267529-A1 | INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS | DILLON MICHAEL PATRICK (US) | 2013-10-10 | — | — | US | claimed |
| US-8476457-B2 | Indole, indazole and benzimidazole arylamides as P2X3 and P2X2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2013-07-02 | — | — | US | claimed |
| EP-2445889-A1 | NOVEL OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES | F. Hoffmann-La Roche AG (CH) | 2012-05-02 | — | — | EP | claimed |
| EP-2445897-A1 | NOVEL INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND/OR P2X2/3 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2012-05-02 | — | — | EP | claimed |
| US-20120083500-A1 | OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES AS P2X3 AND P2X 2/3 ANTAGONISTS | CHEN LI (CN) | 2012-04-05 | — | — | US | claimed |
| US-8093275-B2 | Oxazolone and pyrrolidinone-substituted pryidine amides as P2X3 and P2X2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2012-01-10 | — | — | US | claimed |
| WO-2010149634-A1 | NOVEL INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND/OR P2X2/3 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-29 | — | — | WO | claimed |
| WO-2010149541-A1 | NOVEL OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-29 | — | — | WO | claimed |
| US-20100324070-A1 | INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS | DILLON MICHAEL PATRICK | 2010-12-23 | — | — | US | claimed |
| US-20100324069-A1 | OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS | CHEN LI | 2010-12-23 | — | — | US | claimed |