⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549138 | 0.80 | — | — | |
| SCHEMBL310954 | 0.80 | — | — | |
| SCHEMBL31503961 | 0.69 | APLNR (0.44) | — | |
| SCHEMBL13052072 | 0.69 | APLNR (0.44) | — | |
| SCHEMBL310953 | 0.65 | — | — | |
| SCHEMBL17903 | 0.65 | — | — | |
| SCHEMBL646506 | 0.65 | — | — | |
| SCHEMBL385627 | 0.65 | — | — | |
| SCHEMBL336216 | 0.65 | — | — | |
| SCHEMBL5226 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729089-B2 | Pyrido(3,2-d)pyrimidines useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2014-05-20 | — | — | US | claimed |
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | claimed |
| WO-2008077651-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | claimed |
| US-4287194-A | Compositions with potentiated hypotensive effects | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-09-01 | — | — | US | claimed |
| US-8729089-B2 | Pyrido(3,2-d)pyrimidines useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| WO-2008077651-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |
| US-4287194-A | Compositions with potentiated hypotensive effects | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-09-01 | — | — | US | disclosed |
| US-4287194-A | Compositions with potentiated hypotensive effects | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-09-01 | — | — | US | disclosed |