SCHEMBL5226

SCHEMBL5226

Cc1ccc(Cl)nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30425828 1.00
Ammonia Solution, Strong SCHEMBL27677564 0.97
SCHEMBL111337 0.80
SCHEMBL29367162 0.80
SCHEMBL310954 0.80
SCHEMBL29549138 0.80
SCHEMBL13080532 0.79 LMNA (0.44)
Ammonia Solution, Strong SCHEMBL25301697 0.77
SCHEMBL1456362 0.69 ALDH1A1 (0.46)
SCHEMBL31503961 0.69 APLNR (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1895 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118927-A Synthesis method of 3-chloro-6-methylpyridazine 上海毕得医药科技股份有限公司 2024-12-13 CN claimed
CN-105622519-A 6-methoxy diazine-3-carboxylic acid synthesis process LYU YAN 2016-06-01 CN claimed
CN-103819410-B A kind of preparation method of 6-chlorine pyridazine-3-formic acid JIANGSU XINHAN CO.,LTD. (CN) 2015-09-30 CN claimed
CN-103058933-B Method for industrial preparation of 6-methyl-3-aminopyridazine UNIV QUANZHOU NORMAL 2015-06-17 CN claimed
CN-103819410-A Preparation method for (6-Chloro-pyridazino-3-yl) formic acid SINO HIGH CHINA CO LTD 2014-05-28 CN claimed
CN-103058933-A Method for industrial preparation of 6-methyl-3-aminopyridazine UNIV QUANZHOU NORMAL 2013-04-24 CN claimed
CN-101484444-B Pyridazine compound and use thereof GILEAD SCIENCES INC 2012-11-21 CN claimed
CN-101508677-B Synthesis process of 6-methoxy pyridazine-3- carboxylic acid WUHAN INST TECHNOLOGY 2012-07-25 CN claimed
CN-102432545-A Synthetic method of 3-amino-6-methylpyridazine TAICANG YUNTONG CHEMICAL PLANT 2012-05-02 CN claimed
US-7956184-B2 Pyridazine compound and use thereof GILEAD SCIENCES, INC. (US) 2011-06-07 US claimed
US-20100063059-A1 NOVEL PYRIDAZINE COMPOUND AND USE THEREOF Puerstinger, Gerhard (AT) 2010-03-11 US claimed
EP-2038275-B1 NOVEL PYRIDAZINE COMPOUND AND USE THEREOF GILEAD SCIENCES INC (US) 2010-01-06 EP claimed
CN-101508676-A Synthesis process of 6-methoxy pyridazine-3- carboxylic acid WUHAN INST TECHNOLOGY (CN) 2009-08-19 CN claimed
CN-101508677-A Synthesis process of 6-methoxy pyridazine-3- carboxylic acid WUHAN INST TECHNOLOGY (CN) 2009-08-19 CN claimed
CN-101484444-A Novel pyridazine compound and use thereof GILEAD SCIENCES INC (US) 2009-07-15 CN claimed
EP-2038275-A2 NOVEL PYRIDAZINE COMPOUND AND USE THEREOF Gilead Sciences, Inc. (US) 2009-03-25 EP claimed
US-20080199427-A1 Novel pyridazine compound and use thereof K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) 2008-08-21 US claimed
WO-2008005519-A2 NOVEL PYRIDAZINE COMPOUND AND USE THEREOF GILEAD SCIENCES, INC. (US) 2008-01-10 WO claimed
CN-1021328-C PROCESS FOR PREPARING PYRIDAZINAMINE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 1993-06-23 CN claimed
CN-1033274-A The preparation method of new Pyridazinyl amine derivative JANSSEN PHARMACEUTICA NV (BE) 1989-06-07 CN claimed