Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21823579 | 1.00 | MAPT (0.39) | MAPTTHRBPOLBTDP1L3MBTL1 | |
| SCHEMBL24901706 | 0.94 | FDPS (0.41) | MAPTTHRBPOLBTDP1L3MBTL1 | |
| SCHEMBL21823391 | 0.93 | MAPT (0.42) | MAPTTHRBPOLBTDP1L3MBTL1 | |
| SCHEMBL31096108 | 0.93 | MAPT (0.42) | MAPTTHRBPOLBTDP1L3MBTL1 | |
| SCHEMBL30967302 | 0.93 | HPGD (0.39) | MAPTHPGDRAB9ATSHRKDM4E | |
| SCHEMBL30967300 | 0.93 | HPGD (0.39) | MAPTHPGDRAB9ATSHRKDM4E | |
| SCHEMBL28756202 | 0.83 | MAPT (0.43) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5240512 | 0.83 | ALDH1A1 (0.39) | MAPTPOLBTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL21823526 | 0.81 | FPR2 (0.46) | MAPTTHRB | |
| SCHEMBL21823703 | 0.81 | FPR2 (0.46) | MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166177-B | Boron-containing PDE4 inhibitors | 辉瑞公司 | 2024-09-03 | — | — | CN | disclosed |