SCHEMBL3109628

SCHEMBL3109628

CCCCNCCCc1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.79
DRD2 P14416 1/20 0.59
DRD4 P21917 1/20 0.59
DRD3 P35462 1/20 0.59
KCNH2 Q12809 1/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819750 0.94 SIGMAR1 (0.79) SIGMAR1
SCHEMBL9038092 0.94 SIGMAR1 (0.85) SIGMAR1
Hydrochloric Acid SCHEMBL1677848 0.92 SIGMAR1 (0.82) SIGMAR1MEN1KMT2A
SCHEMBL11096300 0.92 SIGMAR1 (0.82) SIGMAR1
SCHEMBL8625670 0.92 SIGMAR1 (0.81) SIGMAR1
SCHEMBL3119923 0.92 SIGMAR1 (0.82) SIGMAR1
SCHEMBL3122074 0.92 SIGMAR1 (0.82) SIGMAR1
SCHEMBL3115603 0.92 SIGMAR1 (0.82) SIGMAR1
SCHEMBL9819833 0.92 SIGMAR1 (0.82) SIGMAR1
SCHEMBL10064412 0.92 SIGMAR1 (0.76) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215210-A1 DIENE RUBBER COMPOSITION AND METHOD FOR PRODUCING SAME ETIC INC. (JP) 2025-07-03 US disclosed
EP-4502015-A1 DIENE RUBBER COMPOSITION AND METHOD FOR PRODUCING SAME Etic Inc. (JP) 2025-02-05 EP disclosed
CN-118900874-A Diene rubber composition and method for producing same 有限会社ETIC 2024-11-05 CN disclosed
WO-2023190934-A1 DIENE RUBBER COMPOSITION AND METHOD FOR PRODUCING SAME 有限会社ETIC 2023-10-05 WO disclosed
EP-3569593-A1 PRODUCTION OF AMINES VIA A HYDROAMINOMETHYLATION REACTION Universität Wien (AT) 2019-11-20 EP disclosed
EP-3569593-A1 PRODUCTION OF AMINES VIA A HYDROAMINOMETHYLATION REACTION Universität Wien (AT) 2019-11-20 EP disclosed
US-8946302-B2 Selective sigma-1 receptor ligands WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-02-03 US disclosed
US-20130102571-A1 SELECTIVE SIGMA-1 RECEPTOR LIGANDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-04-25 US disclosed
US-8349898-B2 Sigma-1 receptor ligands and methods of use WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-01-08 US disclosed
US-8236965-B2 Benzimidazole derivatives and their use as a medicament IPSEN PHARMA S.A.S. (FR) 2012-08-07 US disclosed
US-20100179111-A1 SIGMA-1 RECEPTOR LIGANDS AND METHODS OF USE WARF - WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-07-15 US disclosed
WO-2010059711-A1 SIGMA-1 RECEPTOR LIGANDS AND METHODS OF USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-05-27 WO disclosed
US-20090170922-A1 Benzimidazole derivatives and their use as a medicament SOCIETE DE CONSEILS DE RECHERECHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) 2009-07-02 US disclosed
US-7495110-B2 Benzimidazole derivatives and their use as GnRH antagonists SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2009-02-24 US disclosed
US-5461155-A Useful in dye diffusion transfer processes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-24 US disclosed
US-5314998-A Dye-donor sheets for thermal printing MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-24 US disclosed
EP-0591016-A1 Organic solvent-soluble metal-azo and metal-azomethine dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-04-06 EP disclosed
US-4987132-A PLATELET ACTIVATING FACTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179111-A1 SIGMA-1 RECEPTOR LIGANDS AND METHODS OF USE SIGMAR1, OPRL1, OPRK1 SIGMAR1 1/4885DRD2 93/4885DRD4 252/4885
US-20090170922-A1 Benzimidazole derivatives and their use as a medicament GNRHR, FSHR, KISS1R SIGMAR1 1040/4885DRD2 750/4885DRD4 669/4885
US-20130102571-A1 SELECTIVE SIGMA-1 RECEPTOR LIGANDS SIGMAR1, OPRL1, OPRK1 SIGMAR1 1/4885DRD2 57/4885DRD4 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.