SCHEMBL31097157

SCHEMBL31097157

[2H]c1ccc2c(cnn2C(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29602247 0.85 RECQL (0.43) RECQL
SCHEMBL493365 0.85 RECQL (0.43) RECQL
SCHEMBL29353925 0.75 PDE1A (0.34) RECQL
SCHEMBL29487819 0.72 TRPA1 (0.39) RECQL
SCHEMBL29520784 0.69 HTR2C (0.50)
SCHEMBL29994445 0.69 RECQL (0.33) RECQL
SCHEMBL30224567 0.68 RECQL (0.42) RECQL
SCHEMBL29520847 0.68 RECQL (0.39) RECQL
SCHEMBL30168550 0.68 CHEK1 (0.38)
SCHEMBL30168569 0.68 CHEK1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294498-A1 FACTOR XIIA INHIBITORS LUNAC THERAPEUTICS LTD (GB) 2024-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240294498-A1 FACTOR XIIA INHIBITORS F11, F13B, F7 RECQL 3169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.