Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17085948 | 0.88 | L3MBTL1 (0.68) | L3MBTL1MAPTMEN1KMT2ABLM | |
| SCHEMBL29441713 | 0.88 | L3MBTL1 (0.68) | L3MBTL1MAPTMEN1KMT2ABLM | |
| SCHEMBL8988 | 0.81 | L3MBTL1 (1.00) | L3MBTL1MAPTMEN1KMT2ABLM | |
| SCHEMBL7710864 | 0.81 | L3MBTL1 (0.68) | L3MBTL1MAPTMEN1KMT2ANOX1 | |
| SCHEMBL31098239 | 0.81 | L3MBTL1 (0.68) | L3MBTL1MAPTMEN1KMT2ANOX1 | |
| SCHEMBL1567426 | 0.81 | L3MBTL1 (0.68) | L3MBTL1MAPTMEN1KMT2ANOX1 | |
| SCHEMBL9007318 | 0.81 | ALDH1A1 (0.68) | L3MBTL1MAPTMEN1KMT2ABLM | |
| SCHEMBL8318228 | 0.80 | NOX1 (0.65) | L3MBTL1MAPTMEN1KMT2ANOX1 | |
| SCHEMBL3176131 | 0.78 | NOX1 (0.68) | L3MBTL1MAPTMEN1KMT2ABLM | |
| SCHEMBL8880299 | 0.77 | SNCA (0.68) | L3MBTL1MAPTMEN1KMT2ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5589474-A | Dibenzothiazepinthione as antiviral agents | GLAXO WELLCOME INC. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0583317-A1 | DIBENZOTHIAZEPINTHIONE AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992019607-A1 | DIBENZOTHIAZEPINTHIONE AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-12 | — | — | WO | disclosed |