Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098801 | 0.84 | POLQ (0.38) | CHRM2CHRM1CHRM3PTGIR | |
| SCHEMBL31098815 | 0.83 | GPR119 (0.41) | MEN1KMT2ANPSR1 | |
| SCHEMBL31098805 | 0.83 | GPR119 (0.41) | MEN1KMT2ANPSR1 | |
| SCHEMBL31098793 | 0.83 | GPR119 (0.41) | MEN1KMT2ANPSR1 | |
| SCHEMBL4386402 | 0.80 | GFER (0.58) | GFERMEN1KMT2ANPSR1PREP | |
| SCHEMBL16361486 | 0.79 | AGTR2 (0.52) | MEN1KMT2AAGTR2NPSR1PREP | |
| SCHEMBL20487600 | 0.79 | AGTR2 (0.52) | MEN1KMT2AAGTR2NPSR1PREP | |
| SCHEMBL16321222 | 0.79 | AGTR2 (0.52) | MEN1KMT2AAGTR2NPSR1PREP | |
| SCHEMBL13318715 | 0.78 | ALDH1A1 (0.44) | AGTR2NPSR1PREP | |
| SCHEMBL464112 | 0.78 | ALDH1A1 (0.44) | AGTR2NPSR1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024191988-A1 | 3,4-FUSED BICYCLIC PYRROLIDINE AND 3,4-FUSED BICYCLIC PYRROLIDINONE COMPOUNDS | CYTEIR THERAPEUTICS, INC. (US) | 2024-09-19 | — | — | WO | disclosed |