Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207273 | 1.00 | LMNA (0.40) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL31207253 | 0.88 | EPHX2 (0.40) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL31099103 | 0.88 | EPHX2 (0.40) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL31207240 | 0.80 | LMNA (0.40) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL31099109 | 0.80 | LMNA (0.40) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL31207239 | 0.79 | LMNA (0.34) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL31207250 | 0.79 | LMNA (0.34) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL31099096 | 0.79 | LMNA (0.34) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL27229519 | 0.77 | MAPT (0.50) | LMNAMAPTSMN1; SMN2TP53KDM1A | |
| SCHEMBL28525675 | 0.74 | LMNA (0.55) | LMNAMAPTSMN1; SMN2TP53KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510780-A | Spiro heterocyclic compounds and uses thereof | 广州必贝特医药股份有限公司 | 2024-08-16 | — | — | CN | disclosed |